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This article examines the genesis of sexual preference. Since human beings as a species are unique in that they have a sexual orientation toward their own gender (homosexuality) as well as the opposite sex (heterosexuality), how or where this preference begins is of interest. This paper examines the research and focuses on how and why some fetuses lack male hormones at the end of pregnancy, which along with stress responses may trigger a high level of activity in the mother's adrenal glands impacting the developing child's later sexual orientation. Options for future research are also discussed.
KEY WORDS: Sexual orientation, heterosexuality, homosexuality, bisexuality.
Allen, L.S., Hines, M., Shryne, J.E., & Gorski, R.A. (1989). Two sexually dismorphic cell groups in the human brain. J Neuroscience, 9, 497-506.
Blanchard, R., & Bogaert, A.F. (1996). Homosexuality in men and number of older brothers. Am. J. Psychiatry, 153, 27-31.
Cameron, N. (1963). Development and psychopathology. Boston, MA: Houghton-Mifflin.
Corna, F., Camperio-Ciani, A., & Capiluppi, C. (October 12, 2004). Evidence for maternally inherited factors favouring male homosexuality and promoting female fecundity. Proceedings of the Royal Society B: Biological Sciences.
Dorner, G. (1972). Sexualhormonabhangige gehirndifferenzierung und sexualitat. New York: Springer-Verlag.
Dorner, G. (1976). Hormones and brain differentiation. Amsterdam: Elsevier/North-Holland Biomedical Press.
Dorner, G. (1977). Hormone dependent differentiation, maturation and function of the brain and sexual behavior. Endokrinologie, 69, 306-20.
Dorner, G., Geier, T., Ahrens, L., et al. (1980). Prenatal stress as possible aetiogenetic factor of homosexuality among human males. Endokrinologie, 75(3), 365-8.
Dorner, G., & Plagemann, A. (2002). DDT in human milk and mental capacities in children at school age: an additional view on PISA. Neuro. Endocrinol. Letter, 23(5-6), 427-31.
Dorner, G., Schenk, B., Schmiedel, B., & Ahrens, L. (1983). Stressful events in prenatal life of bi- and homosexual men. Exp. Clin. Endocrinol., 81(1), 83-7.
Dorner, G. & Staudt J. (1968). Structural changes in the preoptic anterior hypothalamic area of the male rat, following neonatal castration and androgen substitution. Neuroendocrinology, 3, 136-140.
Dorner, G. & Staudt J. (1969a). Perinatal structural sex differentiation of the hypothalamus in rats. Neuroendocrinology, 5, 103-106.
Dorner, G. & Staudt, J. (1969b). Structural changes in the hypothalamic ventromedialnucleus of the male rat following neonatal castration and androgen treatment. Neuroendocrinology, 4, 278-281.
Ellis, L., & Cole-Harding, S. (2001). The effects of prenatal stress, and of prenatal alcohol, and nicotine exposure, on human sexual orientation. Physiol. Behav., 74(1-2), 213-26.
Farabollini, F., Porrini, S., Delia Seta, D., Bianchi, F., & Dessi-Fulgheri, F. (June, 2002). Effects of perinatal exposure to bisphenol A on sociosexual behavior of female and male rats. Environ. Health Perspect., 110 Suppl 3, 409-14.
Freud, S. (1905). Drei Abhandlunger zur Sexualtheorie [three essays on the theory of sexuality]. Leipzig, Germany: F. Deuticke.
Gorski, R.A., Gordon, J.H., Shryne, J.E., & Santham, A.M. (1978). Evidence for a morphological difference within the medial preoptic area of the rat brain. Brain Res., 148, 333-46.
Hamer, D.H., Hu, S., Magnuson, V.L., et al. (1993). A linkage between markers on the X chromosome and male sexual orientatiom. Science, 261, 321-327.
Kardiner, A. (1963). The flight from masculinity. In Ruitenbeek (Ed.), The problem of homosexuality in modern society (pp. 17-39). New York: Dutton.
Kendler, K.S., Thornton, L.M., Gilman, S.E., & Kessler, R.C. (2002). Sexual orientation in a US national sample of twin and nontwin sibling pairs. Am. J. Psychiatry, 157(11), 1843-1946.
Komlos, L., Vardimon, D., Normann, J., et al. (1990). Role of children's sex in mixed mother-child lymphocyte culture reactivity. Am. J. Reprod. ImmunoL, 22, 4-8.
Koo, G.C. (1981). Serology of H-Y antigen. Hum. Genet., 58, 18-20.
LeVay, S. (1991). A difference in hypothalamic structure between heterosexual and homosexual men. Science, 253, 1034-37.
Smitt, J. W. Homosexuality in a new light. International Journal of Sexology, 6, 36-39.
LeVay, S., & Hamer, D.H. (May, 1994). Evidence for a biological influence in male homosexuality. Scientific American, 44-49.
McFadden, D., & Pasanen, E.G. (1998). Comparison of the auditory systems of heterosexuals and homosexuals: Click-evoked otoacoustic emissions. Proceedings of the National Academy of Sciences USA, 95, 2709-2713.
Muller, U., & Lattermann, U. (1988). H-Y antigens, sexual differentiation, and spermatogenesis. Exp. Clin. Immunogen., 5, 176-185.
Perkins, M.W. (1981). Female homosexuality and body build. Archives of Sexual Behavior, 10, 337-345.
Ward, I.L., Ward, O.B., Affuso, J.D., et al. (2001). Fetal testosterone surge: specific modulations induced in male rats by maternal stress and/or alcohol consumption. Harm. Behav., 43(5), 531-9.
Primal Health Research Center, London, England
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