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Controlled trials reveal that, from before conception, nutrient deficits and toxins affect sperm, ovum, and maternal stores, lastingly impairing a child's health and abilities. Deficits, toxins, and stress can inhibit structure and function, and be linked to autism or reduced self-control, possibly with violent tendencies. From the beginning, epigenetic settings are mostly set early for directing development according to current environment. Many are operative in the brain. Nutritional diversion from our evolutionary path, too sudden for genetic adaptation, is resulting in pandemics including mental disorders, cardiovascular problems, obesity, and diabetes. Understanding and practice of nutritional and emotional nurture round the lifecycle helps to fulfill genetic potential. Tracing from the Big Bang, the emergence of elements, nutrients, and cells, providing for the diversity of evolving life, we can see ourselves in context and the biosphere's and our own mutual needs. Vital to both to meet prime needs is a further agricultural revolution, this time of estuary and ocean beds. This article presents the scientific basis for urgent action in this area.

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