There is an increasing body of evidence indicating that prenatal and perinatal
factors predispose to externalizing behavior in the offspring. This paper first reviews recent empirical research
on prenatal and perinatal complications and externalizing behavior. Brain dysfunction mechanisms are then
discussed. It is suggested that (a) birth complications can cause brain damage and (b) brain damage can
predispose to antisocial and violent behavior. Finally, the paper argues that prevention strategies using a
multidisciplinary approach may help reduce prenatal and perinatal complications. In consequence, such
strategies may also help reduce the likelihood of later externalizing behavior problems. KEY WORDS: prenatal
and perinatal complications, birth complications, brain damage, externalizing behavior, antisocial behavior,
violence, prevention.